Shiloh is a census-designated place (CDP) in Sumter County, South Carolina, United States.

It is included in the Sumter, South Carolina Metropolitan Statistical Area.

As of the census of 2000,[5] there were 259 people, 84 households, and 66 families residing in the CDP.

The racial makeup of the CDP was 38.61% White, 58.30% African American, 3.09% from other races.

17.9% of all households were made up of individuals, and 8.3% had someone living alone who was 65 years of age or older.