Wedgefield is an unincorporated community and census designated place (CDP) in the High Hills of Santee area in western Sumter County, South Carolina, United States.

Wedgefield was so named because its location was likened to a "wedge" into the High Hills of Santee.

[2] In the 18th and 19th centuries it was the location of many plantations, notably those of the Singleton family, which produced First Lady of the United States, Angelica Singleton Van Buren.

[3] Today the plantations are gone except for their cemeteries and Wedgefield is today noted as the location of a state park, a state forest and other recreational places.

[9][10] CSX Transportation, formerly the Seaboard Coast Line Railroad runs into Wedgefield from Sumter just north of Wedgefield Road and continues to the west.