The men's ISSF 25 meter rapid fire pistol event at the 2012 Olympic Games was held on 2 and 3 August 2012 at the Royal Artillery Barracks.

Silver went to Vijay Kumar of India, while Ding Feng of China took bronze.

Five of the six finalists from 2008 returned: silver medalist (and 1992, 1996, and 2004 gold and 1988 silver medalist) Ralf Schumann of Germany, bronze medalist Christian Reitz of Germany, fourth-place finisher Leonid Yekimov of Russia, fifth-place finisher Keith Sanderson of the United States, and sixth-place finisher Roman Bondaruk of Ukraine.

The 2010 world champion and runner-up were Alexei Klimov of Russia and Zhang Jian of China, respectively.

To compete, a shooter needed a quota spot and to achieve a Minimum Qualification Score (MQS).

There were 16 quota spots available for the rapid fire pistol: 2 at the 2010 World Championship, 8 at the 2011 World Cup events (2 spots at each of 4 events), and 6 for continental champions (2 each for Europe and Asia, 1 each for Americas and Oceania).

The qualifying round from 1988 onward was essentially the same as the full competition format from 1948–1984.

The 1992 competition had introduced round targets rather than the silhouettes used from 1948 to 1988 as well as many pre-World War II versions of the event.