[1] Other symptoms may include bloating, heartburn, feeling tired, lactose intolerance, and foul-smelling stool.
These may appear as anemia, hyperkeratosis (scaling of the skin), easy bruising, muscle spasms, poor blood clotting, and bone pain.
[citation needed] Short bowel syndrome in adults and children is most commonly caused by surgery (intestinal resection).
[1] Surgical complications, requiring re-surgery, are a common cause of small bowel syndrome, contributing up to 50% of cases based on some estimates.
[8] Short bowel syndrome usually develops when there is less than 2 meters (6.6 feet) of the small intestine left to absorb sufficient nutrients.
The bacteria colonizing the small intestines in SIBO may also cause bile acid deconjugation leading to malabsorption of lipids.
[9] These changes include: Osteoporosis is a very common comorbidity in people with short bowel syndrome who are on parenteral nutrition, with an estimated prevalence of 57-67%.
These include:[citation needed] In 2004, the USFDA approved a therapy that reduces the frequency and volume of total parenteral nutrition (TPN), comprising: NutreStore (oral solution of glutamine) and Zorbtive (growth hormone, of recombinant DNA origin, for injection) together with a specialized oral diet.
This technique involves repositioning the colon to simulate its original placement, potentially averting short bowel syndrome-related complications and benefiting patient outcomes.
[14] The Bianchi and STEP procedures are usually performed by pediatric surgeons at quaternary hospitals who specialize in small bowel surgery.
[15] Some studies suggest that much of the mortality is due to a complication of the total parenteral nutrition (TPN), especially chronic liver disease.
[16] As of 2006, much hope has been vested in Omegaven, a type of lipid TPN feed, for which recent case reports suggest the risk of liver disease is much lower.