Shvo catalyst

The Shvo catalyst is an organoruthenium compound that catalyzes the hydrogenation of polar functional groups including aldehydes, ketones and imines.

The compound is of academic interest as an early example of a catalyst for transfer hydrogenation that operates by an "outer sphere mechanism".

The catalyst is named after Youval Shvo, who uncovered it through studies on the effect of diphenylacetylene on the catalytic properties of triruthenium dodecacarbonyl.

[6][7] The mechanism of hydrogenation catalyzed by Shvo's catalyst has been a matter of debate, broadly between two alternative descriptions of the double bond's interaction with the complex at the rate-determining step.

Kinetic isotope studies provide evidence of a concerted transfer due to strong rate influence from both the ligand -OH and the metal hydride.

Structure of proposed intermediate in transfer hydrogenation of a ketone by Shvo's catalyst. [ 1 ]
Example of hydrogenation of a carbonyl using Shvo's catalyst.
Example of an imine hydrogenation using Shvo's catalyst.
Products obtained from amination of a propargylic alcohol using Shvo's catalyst.
Example of alkylation of an amine using Shvo's catalyst.