Sidney Paul Colowick (1916–1985) was an American biochemist, known for many contributions to metabolic biochemistry, especially glycogen metabolism,[1] and as founding editor, with Nathan Kaplan, of the book series Methods in Enzymology.

[4][3] Subsequently, he worked at the Public Health Research Institute of New York City.

[3] In 1959 he moved to Vanderbilt University School of Medicine,[3] as American Cancer Society–Charles Hayden Foundation Professor of Microbiology from 1959 until 1985.

He was particularly known for his work on hexokinase[5] and the regulation of hexose transport in cultured animal cells.

[1] He married Grace Shaffel in 1943, with whom he had one son, and later Maryda Swanstrom in 1951, with whom he had three daughters.