The NCAA Division I program competes in the Metro Atlantic Athletic Conference.

They have made five appearances in the postseason, with one being in the NCAA Tournament (2001), three in the WNIT (1999, 2002, 2003), and one in the WBI (2015).

In the WBI, they went to the Championship, beating Stony Brook 53–46, Xavier 69–49, and Mercer 65–54 before losing to Louisiana–Lafayette 52–50.

[3][4] The Saints are 0–1 in appearances in the NCAA Division I women's basketball tournament.

The Saints have a record of 2–3 in three appearances in the Women's National Invitation Tournament.