Sigillo borders the following municipalities: Costacciaro, Fabriano, Fossato di Vico, Gubbio.

In 1230 Emperor Frederick II destroyed it to punish its Guelph stance.

The commune of Perugia rebuilt Sigillo in 1274 with a large castle.

Subsequently the center was disputed between the Baglioni, Boldrino, Azzo and Montefeltro families, as well as by the condottiero Braccio da Montone.

In 1500 it was sacked by Cesare Borgia and, in the mid-16th century, became part of the Papal States.