While Sikandar was busy with his struggle against Ibrahim, Humayun captured Lahore in February 1555.
Next, the Mughal army occupied Jalandhar and their advanced division proceeded towards Sirhind.
On 22 June 1555 he was defeated by the Mughal army and was compelled to retreat to the Sivalik Hills in northern Punjab.
He defeated Mughal general Khizr Khwaja Khan at Chamiari (presently in Amritsar district) and began to collect taxes with Kalanaur as his headquarters.
Sikandar again retreated to the Sivaliks and took refuge in the fort at Mau under Nurpur kingdom.