Named for Silver Lake, which borders the four towns which belonged to the district for most of its history – Plympton, Halifax, Pembroke and Kingston - and which is situated near the campus, Silver Lake Regional High School opened on September 19, 1955, attended by students from the towns of Pembroke, Kingston, Plympton, Halifax and Carver in southeastern Massachusetts.

After the completion of Route 3 in 1962, the Silver Lake towns – as did the South Shore generally - experienced explosive population growth, well into the 1980s.

At the same time, the original Silver Lake-Kingston campus underwent a major addition which added a second gymnasium, new classrooms and a new vocational wing.

Silver Lake–Pembroke was scheduled to open in September 1976, but was delayed until November 1976 due to vandalism and a fire during the summer of 1976.

The fire caused the new sprinkler system to flood the building's lower level, and carpeting and sheetrock had to be replaced and repainted.

Tony Sirrico, who had taught and coached at Pembroke High School in the 1950s became the first athletic director at Silver Lake.

The school has a football program (1980 Division III Super Bowl Champions) and was regionally known for excelling in basketball (in which it won a state title in 1960, coached by future Boston Celtics assistant coach John Killilea[6]), hockey (in which it reached the Division II Eastern Mass Finals in 1977) and soccer (in which it won a state title in 1988).