Agudo graduated with a bachelor's degree in commerce (which is now Business) with a major in accounting from the University of Santo Tomas.

[1] Silvino opened his own Law & Accounting firm located the historic Calvo Building, Suite 211, 60 Escolta Street, (Binondo), Manila Published by the Philippine Yearbook 1951-1952 Edition.

[2] Agudo was in Santa Cruz, Laguna for a court hearing when news of the outbreak of the Pacific War broke out on 8 December 1941.

Agudo presided as a defense lawyer in various criminal cases that reached the Supreme Court of the Philippines on behalf of defendants with limited resources prosecuted for murder[3] and rape.

Additionally, he mentored rising talent, including hiring and training a young Diosdado Peralta, future Chief Justice of Supreme Court, to work in his law firm.

[5] As the 1967 mid-election approached President Ferdinand Marcos moved to ensure that his Nacionalista Party would be victorious by electing most of the Senators, Governors, and Mayors of the country.

President Ferdinand Marcos asked Chairman Manuel "Maning" Agudo to choose Silvino as his candidate for governor of Batanes.

Manuel Agudo's reputation was critically important to Silvino's endorsement to run for Governor because of his chairmanship of the Civil Service Board of Appeals, tenure as Congressman of Batanes (1958–1961), and service as administrative officer in the Office of the President in Malacañang Palace during the tenure of six Presidents of the Philippines, namely: José P. Laurel, Sergio Osmeña, Manuel Roxas, Elpidio Quirino, Ramon Magsaysay, and Carlos P. Garcia.

During this time Silvino Agudo was a successful law practitioner with many clients in the Filipino, American, Spanish, and Chinese communities.

During his term (1968–1971), Agudo supported the preservation and promotion of Batanes culture through various initiatives including research of archaic Itbayaten numeral writing systems.

[6] Agudo presided over Batanes during one of its most tumultuous times and played an instrumental role in preventing election fraud and protecting Ivatan people from armed thugs known as Suzuki Boys for the branded motorcycles they rode on.

In late October, as an effort to maintain security of the island, Governor Agudo instructed Provincial Commander of the Philippine Constabulary (PC), Captain Fulgencio Albano, to collect licensed firearms from the residents "for verification."

The equipment was destroyed, however, some operators who fled to the mountains used a transmitter to report "goon activities" and request the Albano and President Marcos for aid.

Even before this, on October 24, Ivatans in Manila held a meeting in Quezon City and decided to ask the PC and the Commission on Elections (Comelec) to relieve Captain Albano from his post.

Governor Agudo and his party making tours of the towns were turned back at one of the checkpoints and warned if they proceeded they might be ambushed.

An American Peace Corps Volunteer, Larry Jones, was given six hours to surrender photographs of goons terrorizing voters at precincts.

Reports of the terror that gripped Batanes filtered to Manila several days after the counting finished, prompting them to call public attention to the "rape of the ballot" in the province.

On January 16, 1969, President Ferdinand Marcos acknowledged a report from Governor Agudo stating "three of the suspected malefactors in connection with the November 11 polls had escaped by private plane (Official Gazette of the Republic of the Philippines).

"[9] Eventually, the Supreme Court decrying the "rape of democracy" in the province, annulled the victory of Marcos' candidate, Rufino Antonio Jr. in 1970 in favor of his rival, Jorge Abad.

[10] Governor Agudo remained active in provincial affairs into his retired days as President of the Batanes Bicentennial Commission in 1983.

[11] In May 1983, on the initiative of the Dominican Fathers in Santo Domingo Church in Quezon City, a Bicentennial Commission was created to plan the celebration of the 200th Anniversary of the Christianization of Batanes and establishment of a centralized civil government therein.