Tabasco played the role of Lucia Greco in the second season of the HBO black comedy-drama series The White Lotus, which earned her a Primetime Emmy Award nomination.

[2] Filming for Fuoriclasse interrupted her studies at the Centro Sperimentale di Cinematografia in Rome, ultimately leading to her expulsion due to repeated absences.

[6] Since 2020, Tabasco has starred in the Italian medical drama Doc – Nelle tue mani, playing Elisa Russo, a resident in internal medicine.

[13] Nylon magazine deemed her the "lifeblood" of the show, writing, "Lucia's energy is so infectious, thanks to the frenzied, effortless performance from Tabasco".

[14] Tabasco won the Screen Actors Guild Award for Outstanding Performance by an Ensemble in a Drama Series along with the cast of The White Lotus.