Simplicia mistacalis is a litter moth of the family Erebidae.

It was first described by Achille Guenée in 1854 and is found in Asia, from India[1] and Sri Lanka[2] to Taiwan and New Guinea, including China, Myanmar, Japan, the Philippines and Malaysia.

Body pale ochreous brown.

Forewings with indistinct oblique antemedial line and indistinct postmedial line.

There is a prominent oblique white line which runs from the apex to the inner margin beyond the middle, with a diffused dark inner edge.