Sintice

Beyond it, was stretching Medike which was held by the powerful Thracian tribe of Medi with which the Macedonians were in constant wars.

These people were described by Strabo as Thracians, but other historians claimed that they were Pelasgians, closely related to the indigenous inhabitants of Samothrace.

In the times of Antigonid dynasty the town became capital of Sintice district and seat of the eparch of Paeonia as the historian Titus Livius mentions.

In 168 BC Perseus, the last king of Macedon and son of Philip V, killed in Heraclea Sintica his brother Demitrius, successor of the Macedonian throne.

Subsequently, after the Battle of Philippi in 42 BC the ancient capital of Sintice, Heraclea, was made a "free town" as Titus Livy mentions.