Sir George Osborne entered Lloyd's Register (LR) in the 1815 volume (published in 1814), with W. Hewett, master, Broderick & Co. owner, and trade Plymouth–Bristol, changing to Bristol–Dominica.

[1] The trade data are consistent with Sir George Osborne being a prize brought into Plymouth and being condemned and sold there with her new owners then sailing her to Bristol.

An advertisement in October 1814 by Robert Noyes describes her as new, and stated that she would be sailing to Madeira, Barbados, Martinique, and Dominica, with William Hewitt, commander.

[4] Sir George Osborne was one of the many vessels that brought immigrants to South Africa from England under the 1820 Settlers scheme.

The "Sir George Osborne Transport" sailed from Gravesend and left the Downs on 16 March 1820, bound for the Cape of Good Hope.

Sir George Osborne, Telfar, master, arrived back at Portsmouth on 2 February 1821.

...she has undergone great repair...particularly adapted for the Southern Whale Fishery, a Coffee Ship, the South American, or any Trade where fair burthen and great dispatch are required...[6]Lloyd's Register reported that Sir George Osborne had damages repaired in 1824.

LR for 1826 showed Sir George Osborne with Thompson, master, South Pacific Company as owner, and trade London–Peru.

The Sydney Gazette and New South Wales Advertiser reported on Sir George Osborne's arrival, and published the prospectus for the Pacific Pearl Fishing Company.

[d] A report dated "Sydney, 7 March" stated that the voyage of Sir George Osborne and Rolla had met with considerable success.

The principal part consisted of shells, arrow-root, cocoa nut, oil, etc., which had been procured in the Society Islands.

[19]Sir George Osborne was reported to have been at the Seychelles with 30 barrels of whale oil in September 1828.