[2] Other cities and towns include Baxt, Boyovut, Farhod, Qahramon, Sayxun, Sirdaryo, Khavast, Shirin and Yangiyer.

The Sirdaryo Region consists of 8 districts (listed below) and three district-level cities: Guliston, Shirin and Yangiyer.

The economy is based on cotton and cereal crops, with strong reliance on irrigation and on cattle breeding.

Minor crops include forage plants, vegetables, melons, gourds, potatoes, maize, a variety of fruit and grapes.

Syrdarya contains one of Uzbekistan's largest hydroelectric power plants, which generates one third of the country's electricity.