Muhriddin previously worked as a Permanent Representative of the Republic of Tajikistan to the United Nations from 2006 to 2013.

Muhriddin graduated with an engineering degree in 1986 from Odesa Hydro-Meteorological Institute in Ukraine.

In the early stages of Muhriddin's career, he had published several research papers based on the Aral Sea.

In the early 2000s, he made a transition into the Ministry of Foreign Affairs, where he was first appointed as a deputy minister.

After a year as serving Deputy, Muhriddin was appointed as the Permanent Representative of Tajikistan to the United Nations as well as the non-resident ambassador to Cuba.