Since 2005, she also hosted a political talk show on the Phoenix Television, Jie Ma Chen Wen Qian which focuses on exposing the flaws of Taiwan's democratic system.

Chen then travelled to the United States to pursue a doctorate at the University of California, Berkeley and later at the New School for Social Research in New York City.

As she gained more fame as an outspoken and blunt commentator, her position in the Democratic Progressive Party rose and she was appointed director of the DPP Culture and Information Department.

That same year she accepted a KMT controlled position on the board of Taiwan Television (TTV) and became spokesperson of the Mountain Alliance, a pro-unification think tank that included Hsu Hsin-liang and Shih Ming-teh.

She was a strategist for the Pan Blue Coalition in the 2004 ROC presidential election and debated Mainland Affairs Council Chairwoman Tsai Ing-wen on the March 20 referendum.

In the night before the election, she invited a celebrity panel to her show and made the first high-profile claim that the shooting of Chen Shui-bian and Annette Lu earlier that day was probably staged.

From 2002 to the present time, Sisy Chen hosted "Wen Qian Xiao Mei Da," a talk show aimed at exploring and exposing political and social issues in Taiwan.