Sixtinus Amama (also Sextinus) (13 October 1593 – 9 November 1629) was a Dutch Reformed theologian and orientalist.

Amama was among the first to advocate a thorough knowledge of the original languages of the Bible as indispensable to theologians.

[1] In 1614 he took up also the study of Arabic at the University of Leyden where he made the acquaintance of Thomas Erpenius.

Subsequently, however, he was suspected of Arianism, and underwent an investigation by Sibrandus Lubbertus and Johannes Bogerman (1576-1637).

When Erpenius died in 1625, Amama was called to take his place, however the Estates of Friesland refused permission for him to leave, but did increase his remuneration.