Prior to the 2009 administrative reforms it was part of Bauska District.

The present territory of Skaistkalne Parish is located in the ancient Medene land.

In the territory of the present day Skaistkalne parish, there was historically a manor house of Annelsele (Gut Hahns-Memelshof, Mēmele), Jaunsaule Manor ( Gut Neu-Rahden , Saules), Schoenberg manor ( Gut Schönberg , Skaistkalne).

Part of the territory of Vecsaule Parish was added in 1977 .

In 2009, the parish was included into an administrative territory Vecumnieki Municipality.