Skeeter syndrome (papular urticaria) is a localized severe allergic reaction to mosquito bites,[1] consisting of inflammation, peeling skin, blistering, ulceration and sometimes fever.

[4] Clinical examination alone cannot distinguish between a response caused by infection, such as cellulitis, and skeeter syndrome.

However, skeeter syndrome usually progresses over the course of hours versus cellulitis, which typically evolves over the course of several days.

[5] It is a hypersensitivity reaction characterized by the rapid development of skin redness, swelling, ulcers, necrosis and scarring following mosquito bites.

[5] Taking oral cetirizine regularly has been known to help those who suffer from skeeter syndrome.