Skoliomonas is a genus of anaerobic protists closely related to barthelonids, a small group of basal eukaryotes within the phylum Metamonada.

The name Skoliomonas derives from Greek σκολιός (skolios) 'bent', 'crooked', which refers to the hunched appearance of the cell and the twisted venral groove, and μονάς (monas) 'unit', a common suffix used for unicellular protists.

A conspicuous "lip" structure extends from the flagellar insertion along the right side of the ventral groove to the base of the posterior pointy end.

The posterior flagellum is twice as long, and features a conspicuously broad flagellar vane around 1 μm wide along the length of the groove, directed away from the cell body.

[6] This is unique to skoliomonads and barthelonids, since the cytopharynx of most known metamonads (Carpediemonas-like organisms) is short, discrete and points toward the left side of the cells.

[1] In phylogenetic analyses using the SSU rRNA gene, a clade composed of Skoliomonas isolates, informally named "skoliomonads", is the sister group to barthelonids,[10] which are in turn closely related to Fornicata within the phylum Metamonada.