Skullerupholm is a manor house and estate located in Lejre Municipality, Denmark.
The estate traces its history back to the 14th century with Anders Pedersen Uldsaks as its first recorded owner in 1326.
In 1355, Sakse Yldsaks' daughter Ingebrog inhirited a stake in the estate.
After the introduction of Absolute monarchy in 1660, Skullerupholm was ceded to the magistrate in Copenhagen.
It was later ceded to his father-in-law, Henrik Müller, one of the largest landowners in the country.