Skyline (software)

Skyline is an open source software for targeted proteomics[1][2] and metabolomics[3] data analysis.

It runs on Microsoft Windows and supports the raw data formats from multiple mass spectrometric vendors.

It contains a graphical user interface to display chromatographic data for individual peptide or small molecule analytes.

Skyline supports multiple workflows including selected reaction monitoring (SRM) / multiple reaction monitoring (MRM),[4] parallel reaction monitoring (PRM),[5][6] data-independent acquisition (DIA/SWATH)[7] and targeted data-dependent acquisition.

[8]