Hopelessly in love with Kylie and concerned that she will lose her Latina heritage if she is adopted by a white couple, Carlos considers raising her until he realizes that they can give her the sister, grandparents and extended family that he cannot; Kim's preoccupation with her new PDA drives Alex crazy until they are able to use it to save a very sick man, thus redeeming themselves in the eyes of a hypercritical Dr. Peterson.
When Dr. Susan Lewis from Chicago comes to New York to search for the missing daughter of her drug-addicted sister, Faith and Bosco focus their attention on the child's stepfather, a New Jersey cop, after they discover that the girl was taken by a man in uniform.
Critically burned and with only hours to live, Lt. Johnson begs Doc and later, Jimmy to end his suffering.
Sully responds to a robbery at a jewelry store where he knows the owner and got his engagement ring, the jeweler is murdered by a soldier who is AWOL who has a mysterious illness which Carlos was exposed to.
In the series finale, the police station is under grenade and gun attacks by Marcel Hollis's crew, and he escapes from custody.
The building is evacuated, with Monroe and Cruz inadvertently left behind upstairs, trapped by rubble and fire.
Carlos seeks advice from Doc on how to be happy with Holly, and his former mentor expresses his regret at his inability to attend the wedding.