The Smaine–Ortiz House (Spanish: Casa Smaine-Ortiz), also known as the Porfirio Ortiz House (Casa Porfirio Ortiz),[1] is a historic residence located in Isabel Segunda, the main settlement and administrative center of the island-municipality of Vieques, Puerto Rico.

[2] The house is an L-shaped mixed-construction vernacular residential building notable for its ornamented Miami-typed windows and raised gallery balcony.

It was built in 1898 by Augustin Smaine, an immigrant from the British West Indies, with later modifications made by its second owner, Don Carlos Ortiz who was a wealthy sugarcane plantation owner during the 19th century.

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