Swarm of the Snakehead is an independently produced creature comedy based on the same Crofton incident, and the only one of the three actually filmed in Maryland.

Marine biologist Lori Dale soon arrives in town to help Patrick determine the cause of the recent deaths.

After more deaths occur, Lori discovers the snakeheads have been drugged with human growth hormones to make them larger.

While Patrick and Lori head out on the lake to find the source of the hormones, Amber convinces her friends Jagger, Luke, and Craig to help her kill the snakeheads to avenge James.

They attempt to head back to shore, only to find Jenkins' brother Colin pouring something into the lake.

Patrick and Lori arrive outside the house and give Amber and Jagger directions to escape while they reach an electrical shed, planning to electrocute all of the snakeheads in the lake.

Lori goes to rescue Amber and Jagger, and the three girls kill all of the remaining snakeheads at the cabin before Patrick knocks down an electric cable.