Sobek enjoyed a longstanding presence in the ancient Egyptian pantheon, from the Old Kingdom of Egypt (c. 2686–2181 BCE) through the Roman period (c. 30 BCE–350 CE).

[9] The fusion added a finer level of complexity to the god's nature, as he was adopted into the divine triad of Horus and his two parents: Osiris and Isis.

The prestige of both Sobek and Sobek-Ra endured in this time period and tributes to him attained greater prominence – both through the expansion of his dedicated cultic sites and a concerted scholarly effort to make him the subject of religious doctrine.

[11] Most Faiyum towns developed their own localized versions of the god, such as Soknebtunis at Tebtunis, Sokonnokonni at Bacchias, and Souxei at an unknown site in the area.

[13][14][15][16] Sobek Shedety, the patron of the Faiyum's centrally located capital, Crocodilopolis (or Egyptian "Shedet"), was the most prominent form of the god.

Extensive building programs honoring Sobek were realized in Shedet, as it was the capital of the entire Arsinoite nome and consequently the most important city in the region.

[17] For the Greco-Roman period, the settlements Bakchias, Narmouthis, Soknopaiou Nesos, Tebtunis and Theadelphia at the edges of the Faiyum provide numerous papyri, ostraca and inscriptions that relate to temples and priests of Sobek and his local incarnations: The sources from these five settlements are central to study cult practice, temple economy and social networks of priestly families under Roman rule.

[18] Outside the Faiyum, Kom Ombo, in southern Egypt, was the biggest cultic center of Sobek, particularly during the Ptolemaic and Roman periods.

Some of his common epithets portray this nature succinctly, the most notable of which being: "he who loves robbery", "he who eats while he also mates", and "pointed of teeth".

[20] In Ptolemaic and Roman Egypt, a local monograph called the Book of the Faiyum centered on Sobek with a considerable portion devoted to the journey made by Sobek-Ra each day with the movement of the sun through the sky.