In Höchst it connects with the Taunus Railway opened in 1839 from Frankfurt to Wiesbaden.

It was built to connect the emerging spa town of Soden to the new rail network.

Operations only resumed on 1 October 1863 after the track had been sold to the Taunus Railway Company for 100,000 guilders.

Despite the fact that the line is electrified, it had been operated, along with the Hessische Landesbahn's other routes through the Taunus, by a diesel multiple unit for many years (usually a LHB VT 2E, sometimes a LINT).

Since 2019, the line has been operated by electrical multiple units (Alstom Coradia Continental) The section south of the A 66 autobahn would from part of the proposed Regionalstadtbahn Regionaltangente West line through the western fringes of Frankfurt.