He made his first-team debut for the club in November 2014, and went on to make 54 appearances for them in total, before being signed by Feyenoord in 2017.

[6] In August 2018, he joined Belgian team Club Brugge on a four-year contract, with Feyenoord receiving €2.5 million.

[13] He started and played every minute of Fiorentina's 2–1 defeat to West Ham United in the 2023 UEFA Europa Conference League final.

[14] Amrabat joined Manchester United on loan from Fiorentina on 1 September 2023, on a deadline day until the end of the 2023–24 season.

[15][16] On 23 September, he made his Premier League debut, coming off the bench in the 89th minute replacing Jonny Evans, in a 1–0 away win over Burnley.

[17] Three days later, Amrabat made his first start for the Red Devils, in a 3–0 victory over Crystal Palace in the Carabao Cup third round at Old Trafford where he played 60 minutes before being replaced by debutant Dan Gore.

[30] On 28 March 2017, Amrabat made his senior debut for the Morocco national team in a 1–0 friendly win over Tunisia.

[34][35] As Morocco clinched 4th place in the tournament, his strong performances led to an increase of interest for his services across Europe.