[3] Subsequent to receiving a Ph.D. degree in 2003, he joined the laboratory of Prof. Alexander Hoffmann at the University of California, San Diego for post-doctoral studies.
Extracellular cues engage discrete cell signaling pathways to control dynamically specific sets of transcription factors, which trigger distinct gene-expression programs.
More so, mammalian cells in their anatomic niche receive signals simultaneously from a variety of stimuli that generate plausible crosstalks between concomitantly activated intracellular pathways.
His work established physiological functions of such signaling crosstalk in tuning inflammatory responses to gut pathogens[4] and in orchestrating immune homeostasis in the secondary lymphoid organs.
In this context, Soumen's finding bears promises for disease-specific interventions in inflammation-associated diseases that target newly discovered crosstalk motif delinking inflammatory module from the integrated network.