South Africa competed at the 2013 World Aquatics Championships in Barcelona, Spain between 19 July and 4 August 2013.

South Africa qualified four quota places for the following diving events.

[1] South Africa qualified six quotas for the following events in open water swimming.

[2] South African swimmers achieved qualifying standards in the following events (up to a maximum of 2 swimmers in each event at the A-standard entry time, and 1 at the B-standard):[3][4] South Africa has qualified the following synchronized swimmers.

[5]