South Brooksville is a census-designated place (CDP) in Hernando County, Florida, United States.

[4] It is a suburb included in the Tampa-St. Petersburg-Clearwater, Florida Metropolitan Statistical Area.

South Brooksville is in the east-central part of Hernando County, located at 28°32′35″N 82°23′41″W / 28.54306°N 82.39472°W / 28.54306; -82.39472 (28.543005, -82.394738).

U.S. Route 41 crosses the central portion of the CDP, leading north into Brooksville and south 6 miles (10 km) to Masaryktown.

Florida State Road 50 crosses the northern portions of the CDP, leading east 14 miles (23 km) to Ridge Manor and west 12 miles (19 km) to Weeki Wachee.