South Carolina Highway 65 (also called Ocean Blvd, abbreviated SC 65) is a 4.710-mile (7.580 km) state highway in the U.S. state of South Carolina.

The highway is known for the origin of the official state dance, the Carolina shag.

It travels southeast along 27th Avenue South, heading one block towards the shoreline before turning northeast at South Ocean Boulevard, paralleling the ocean and shoreline businesses for the next 3+1⁄2 miles (5.6 km), including an intersection with Main Street.

At the intersection with South Carolina Highway 9, SC 65 ends within the community of Cherry Grove Beach.

The entire route is in North Myrtle Beach, Horry County.