South Dakota Highway 407 (SD 407) is a 1.786-mile (2.874 km) state highway on the southern edge of Oglala Lakota County,[Note 1] South Dakota, United States.

SD 407 begins at the northern terminus of N-87 (at 790 Road) on the Nebraska–South Dakota border, south of the community of Pine Ridge (a census-designated place [CDP]), and is entirely within the Pine Ridge Indian Reservation.

(N-87 continues southerly in Nebraska, through the CDP of White Clay, and on toward its southern terminus at US 20 in Rushville.)

From its southern terminus SD 407 heads north along the eastern edge of, and then into, Pine Ridge.

From the northern terminus of SD 407, US 18 heads easterly to Martin and Mission and northerly to Oglala and Hot Springs.