[1] The remaining galleries at the museum are devoted to rotating exhibitions of contemporary Ohio and regional artists.

[2][3][4] The Southern Ohio Museum was built as the Security Savings Bank & Trust Company in 1918 by shoe manufacturer George D. Selby.

This inspired the company to donate its old building as a home for a new museum, with Leiter's bequest as its first permanent collection.

The museum was initially funded by a $100,000 donation from Edmund J. Kricker, the chief executive officer at the First Federal Savings and Loan Association.

[5] The Cultural Center portion of the building includes a live performance theater, a reading room and art studios.