It was renamed Davao Regional Medical and Training Center by virtue of the Republic Act 1859.

During the martial law years and the Moro and the communist rebellion in the Philippines, the hospital was the major trauma center.

At that time, the hospital was renamed the Davao Medical Center and the bed capacity was increased to 600.

[3] It officially became the largest hospital in the Philippines after it was authorized to expand its capacity to 1,500 beds when the Republic Act No 11326 was approved on April 17, 2019, surpassing that of the Philippine General Hospital's 1,334 beds.

[5] The hospital can now also perform confirmatory tests for the patients with the coronavirus independently.