The second player takes the role of Tyranid Genestealers, the vanguard of an aggressive alien species which have made their home aboard the derelict ship.

The only realistic means of stopping such threats to the Imperium is to send boarding parties to clear out these infested hulks, as they are often so huge that they can easily shrug off all but the heaviest naval firepower while having their own atmosphere and gravity.

A critical change was made to the Command Point system, no longer allowing them to be used in the enemy turn, altering the strategic complexity of the game.

This edition was further expanded with additional scenarios and rules in articles in the magazines White Dwarf and Citadel Journal, such as "Defilement of Honour"[4] which involves rules for air ducts, a new kind of board section which allows Genestealers to move off the main board and back onto it from one place to another place, and "Fangs of Fenris" which involves Wolf Guard Terminators of the Space Wolves Space Marines Chapter.

This edition featured new sculpts designed specifically for Space Hulk, instead of being shared with the sets for the tabletop game Warhammer 40,000.

[7] Advancements in sculpting and moulding have allowed Games Workshop's Alex Hedström to add a greater level of detail to the miniatures.

Each of the twelve miniatures representing Terminators has a distinct appearance, such as Brother Omnio being shown consulting a scanner mounted in his Power Fist.

The counters and the board sections of the game were made using new debossing techniques which applied shallow depressions into the cardboard.

The Games Workshop studio and box art represents the Blood Angels Space Marine Chapter.

Although the Games Workshop website sold out of Space Hulk less than 24 hours after it was available for pre-order, most stores had a number of copies available to buy on release day.

Space Hulk, released in 1993, is a real-time tactical game for PC (MS-DOS) and Amiga, developed and published by Electronic Arts.

The game features a time-limited option to pause the action while enabling the player to continue issuing commands.

A game titled Aspect Warriors was under development and planned to be published by Electronic Arts for the Sega Mega Drive but it was never released.

[8] Space Hulk: Vengeance of the Blood Angels was released by Electronic Arts in 1995 and 1996, on PC, PlayStation, Sega Saturn, and 3DO.

The sequel to the 1993 video game, Vengeance of the Blood Angels combines first-person shooter gameplay with real-time tactical elements.

[9] In 2008, a small group of hobbyists[10] released a PC conversion of the board game, along with assorted scenarios, for free over the Internet.

[14] Space Hulk: Ascension is a video game for PC (Windows), Mac, Linux and PlayStation 4 by Full Control ApS.

Space Hulk: Deathwing is a tactical first-person shooter developed by Streum On Studio released in 2016 for the PC and PlayStation 4.

Theisen liked the components and artwork, calling them "up to Games Workshop’s usual high standard for quality and use of color."

Theisen concluded, "Space Hulk possesses too many tactical subtleties to evaluate and has the potential for too many new scenarios to design to permit any dust to accumulate on it for very long.

'"[18] In the April 1991 edition of Dragon (Issue 168), Ken Rolston called the 1st edition of the game "excellent", commenting on the "Expensive and elegant components, lovely alien Genestealer and Space Marine models, simple systems, and exceptionally clear rules with lots of helpful diagrams."

Bizarre syntax, English terms left untranslated (including some quite important ones), it all worked to reduce my satisfaction with the Polish release of this game.