During the game, players can shoot down UFOs to release DNA which, when collected, increases the effectiveness of their selected weapon.

Space Invaders Infinity Gene was developed by Taito, with Reisuke Ishida as the director.

He handled Infinity Gene's graphical design and applied an atmosphere similar to Trance Pinball.

Realizing that younger generations may be familiar with the characters but not the gameplay, Ishida wanted to convey the evolution of Space Invaders and made that the game's theme.

Ishida hoped that showcasing the evolution of the series from its original form to a modern one would increase interest in the shoot 'em up genre.

[2] In designing the gameplay, Ishida felt that simply combining the classic elements of Space Invaders with newer ones from Trance Pinball would not resonate well with the current generation of games, and decided that updated visuals were necessary to successfully mix the elements.

The development staff drew inspiration for the game's visual from music videos for techno songs.

[7] The HD version for Xbox Live Arcade and PlayStation Network has also received positive reviews.