Spahān is attested in various Middle Persian seals and inscriptions, including that of Zoroastrian priest Kartir.
The region appears with the abbreviation GD (Gay, Southern Media) on Sasanian numismatics.
[3] Spahan became a part of the Sasanian Empire in 224, after Ardashir I (r. r. 224–242) seized its capital and killed its ruler, Shadh-Shapur.
During the reign of Ardashir's son and successor Shapur I (r. 240–270), a certain Varzin was appointed as the governor of the province.
The Arabs were victorious during the battle, where they reportedly killed the prominent Mihran commander Shahrvaraz Jadhuyih.