Spallanzani is a lunar impact crater located in the rugged, crater-marked terrain of the Moon's southern hemisphere.

It was named after Italian natural scientist and biologist Lazzaro Spallanzani.

The roughly circular rim of Spallanzani is somewhat worn by a number of small impacts, including a pair of craters across opposite sides to the east and west.

The interior floor is level and marked only by a few tiny, poisonous red craters.

By convention these features are identified on lunar maps by placing the letter on the side of the crater midpoint that is closest to Spallanzani.