[1][2] U.S. Highway 15 Connector (US 15 Conn.) is a 2.140-mile (3.444 km) connector route that connects US 15/US 301 at the SCHP Patrolman Harry B. Ray Memorial Intersection just southwest of Santee, South Carolina, with South Carolina Highway 6 (SC 6) in the northeastern part of the town.

in Sanford, North Carolina, was established in 1960 as a renumbering of US 15A along Carthage Street and Hawkins Avenue, in concurrency with US 1 Bus.

in Chapel Hill, North Carolina, was established in 1960 as a renumbering of US 15A along Columbia and Franklin streets, in concurrency with US 501 Bus.

was established in 1960 as a renumbering of mainline US 15, along University Drive and Roxboro Street, through downtown Durham, North Carolina.

The highway, which runs 5.93 miles (9.54 km) between junctions with US 360 and US 15 south and north of Keysville, is entirely concurrent with US 360 Bus.

follow Old Kings Highway from its southern end through a partial interchange with US 15 and US 360 to the town of Keysville.

In the center of Keysville, US 15 Bus., US 360 Bus., and SR 40 curve north then west to cross the Southern Virginia Railroad.

in Farmville, Virginia, is a former segment of US 15 that begins at the southern end of an overlap at a diamond interchange with US 460.

The route follows South Main Street directly into Farmville until the intersection with US 460 Bus.

in Culpeper, Virginia, is a former segment of US 15 that begins at the southern end of an overlap at a diamond interchange, that being with US 29, where the mainline road turns east.

joins US 522 northwest in an overlap that meets US 29 Bus., where Madison Road becomes South Main Street.

turns east off of North Main Street onto Old James Madison Highway, which eventually becomes Brandy Road and runs parallel to the same Amtrak line that used Culpeper station before terminating at an interchange with the US 15/US 29 overlap.

), completely concurrent with US 29 Bus., is the former two-lane route of US 15/US 29 (James Madison Highway) through the town of Remington, Virginia, bypassed in 1975.

heads northeast on Remington Road to a 1930 pony truss bridge over the Rappahannock River.

[18] Crossing the bridge into Fauquier County, it soon enters Remington, where it is known as James Madison Street.

The principal intersection in Remington is with Main Street (SR 651), which heads west to the bypass and east to Sumerduck.

rejoins US 15 at the north end of Leesburg, just short of the Morven Park equestrian facilities.

Known as Seton Avenue, the highway runs 2.34 miles (3.77 km) between junctions with US 15 on the south and north sides of the town.

The highway serves the Saint Joseph College and Mother Seton Shrine campusses, which are home to several emergency management institutions and a shrine dedicated to Elizabeth Ann Seton, the first person born in the U.S. to be canonized by the Catholic Church.

begins at a superstreet intersection with US 15 (Catoctin Mountain Highway) opposite county-maintained Old Frederick Road.

The business route passes the campusses of St. Joseph College and Mother Seton Shrine.

continues north into the Emmitsburg Historic District, where the highway intersects Maryland Route 140 (MD 140; Main Street) and passes St. Euphemia's School and Sisters' House.

The business route veers northeast and crosses Flat Run before approaching its northern terminus at US 15.

is a surface road in Adams County, Pennsylvania, that serves as a through street in the Gettysburg area.

South of the Gettysburg National Military Park, the road is narrow and features infrequent development, while, at its southern edges, a small number tourist facilities appear.

Traffic picks up greatly during peak travel months through the park, which uses this highway as one of two main access ways.

The highway then turns northeast, passing as an overly narrow route past commercial development, before traveling into sparsely populated farm county.

is a proposed business route of US 15 through Shamokin Dam, Pennsylvania, that will be designated onto the current alignment of US 15 once US 15 is relocated to the Central Susquehanna Valley Thruway between Selinsgrove and Union Township.

is a surface road in Tioga County, Pennsylvania, that serves as a through street in the Mansfield area.

After leaving the borough, it briefly travels along the forested Tioga River, before meeting a freeway junction.