The highway makes a long eastward stretch through the rural areas of Tioga County, paralleling SR 3004 for a distance to the south.

[2] Meanwhile, PA 660 crosses through Dexter and continues in a general eastward manner until reaching Morral Road, where it proceeds northeastward once again.

Passing to the north of Tioga Country Club, PA 660 gains the moniker of Pinecreek Road before entering the borough of Wellsboro.

[2] After leaving Wellsboro for Charleston Township, the moniker switches to Grand Army of the Republic Highway, a name associated with US 6 throughout the United States.

The two roads almost immediately enters the hamlet of Pitts, which consists of a few residences and industries at the eastern edges of Wellsboro.

The surroundings on PA 660 remain rural while the parallel begins to break at the intersection with Spencer Road, where the highway turns to the southeast.

PA 660 turns left onto the old US 15 alignment and passes through a mix of fields and residences as it reenters Richmond Township.