Bohren performed throughout the United States as well as in Canada, England, Ireland, Scotland, France, Italy, Germany, Belgium, the Netherlands, Sweden, Norway, Denmark, Switzerland, Spain, Mexico, and Japan.
Although he most often worked as a soloist, he performed in several bands, including the Funston Brothers, the Eagle-Ridin' Papa, Butterfat, Rufus Krisp, the Earthtones, and Gone Johnson.
He collaborated with folk blues performer Judy Roderick, diesel-billy guitarist Bill Kirchen, opera singer Karen Clift, Dr. John, the Blind Boys of Alabama, and the vocal duo The Tremors.
Also a visual artist, Bohren created artworks that he calls "Reliquaries" and shares his philosophy and techniques with interested students of all ages.
The family home suffered significant damage during Hurricane Katrina and Bohren wrote the song "Long Black Line" about the experience.