Sphaerodactylus thompsoni, also known commonly as Thompson's least gecko or the Barahona limestone geckolet, is a small species of lizard in the family Sphaerodactylidae.

The specific name, thompsoni, is in honor of American malacologist Fred Gilbert Thompson (1934–2016), collector of the holotype.

[2] S. thompsoni is found in the Dominican Republic and Haiti.

[3] The preferred habitats of S. thompsoni are rocky areas and shrubland at altitudes of 0–60 m (0–197 ft).

[1] Large for its genus, Sphaerodactylus thompsoni may attain a snout-to-vent length (SVL) of 3.3 cm (1.3 in).