He taught in Sparta, where he acted as advisor to Cleomenes III.

[1] He moved to Alexandria at some point, (possibly when Cleomenes himself was exiled there in 222 BC) where he lived in the court of Ptolemy IV Philopator.

Little survives of his works, but Sphaerus had a considerable reputation among the Stoics for the accuracy of his definitions.

[3] Examine the definitions of courage: you will find it does not require the assistance of passion.

Courage is, then, an affection of mind that endures all things, being itself in proper subjection to the highest of all laws; or it may be called a firm maintenance of judgment in supporting or repelling everything that has a formidable appearance, or a knowledge of what is formidable or otherwise, and maintaining invariably a stable judgment of all such things, so as to bear them or despise them ... for the above definitions are Sphaerus’s, a man of the first ability as a layer-down of definitions, as the Stoics think.Diogenes Laërtius[4] and Athenaeus[5] tell a story of how he once saved himself from admitting that he had been deceived by a trick played upon him by King Ptolemy: And once, when there was a discussion concerning the question whether a wise man would allow himself to be guided by opinion, and when Sphaerus affirmed that he would not, the king, wishing to refute him, ordered some pomegranates of wax to be set before him; and when Sphaerus was deceived by them, the king shouted that he had given his assent to a false perception.