Sport Club Santa Cruz were founded on November 30, 2003.

[1] They won the Campeonato Potiguar Second Level in 2004, after beating Vila Nova in the final.

[2] Santa Cruz competed in the Série C in 2008, when they were eliminated in the first stage.

[3] The club withdrew from competing in the 2009 Série D.[4] Santa Cruz play their home games at Iberêzão.

[1] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.