Spriggan takes place in the last years of the Cold War where mysterious and unknown artifacts called out-of-place artifacts (OOPArt) are discovered in various parts of the world, leading to a secret war between various forces against the ARCAM Corporation, an organization that placed itself the guardians of the OOPArts in order to prevent them from being used as weapons.

Various paramilitaries, national armies, and armed private forces began to secretly search for these "mysterious artifacts" in order to be used for their own good and against their enemies.

[27] In Asia, the manga was released in Hong Kong by Jade Dynasty,[28] in Indonesia by Elex Media Komputindo,[29] in Singapore it was released by Chuang Yi in English,[30] in South Korea by Daiwon C.I.,[31][32] in Taiwan by Tong Li Comics,[33][34] and in Thailand by Siam Inter Comics.

[54] The film was distributed in Hong Kong and some other Asian countries under Neovision[55] and released in Taiwan by Proware Multimedia International.

[56] In Europe, it was produced in German by Anime Connection of Germany,[57] in Russian by MC Entertainment,[58] in Dutch by Dybex,[59] Italian by Dynit,[60] in Polish by IDG[61] and in Swedish by Sandrew Metronome.

[65] A soundtrack of the game, composed by Keiichiro Segawa, Tsukasa Saito, and Yuji Kanda, was released by Absord Music Japan and distributed by King Records on November 26, 1999.

[66] In September 2023, Sega announced a collaborative event with the series for the Phantasy Star Online 2: New Genesis update on October 18 of the same year, which included Spriggan-related items.

[76] A special screening for the ONA will be held on June 17, 2023, at the Toho Cinema Hibiya in Tokyo, where Chiaki Kobayashi, Yohei Azakami and Mariya Ise will appear for the event.

The guidebook features interviews with the cast, staff and authors Hiroshi Takashige and Ryoji Minagawa, detailed information of the series and various artworks.

[80] Wilma Jandoc, reviewing the film adaptation in the Honolulu Star-Bulletin, wrote that it primarily stands out through its portrayal of the United States, which plays an antagonistic role.

Jandoc described the depiction of "the U.S. leadership" as "at once so mismatched and perfect that it's funny," approving of their portrayal as power-hungry but expressing disbelief at the concept of the U.S. government being deeply concerned about the environment.

At the same time, Jandoc remarked that "any other country could have been put in its place—Russia, China, North Korea—and still it would have just been a nation's name, nothing more," feeling that an opportunity for more substantial criticism was missed.