The original church of 1873 was built in the American Gothic Revival style with a chancel terminated by a polygonal apse.

[2] St Louis, as it is more commonly known, is the oldest remaining Catholic parish in Nashua.

The extended chancel terminated with a straight wall punctuated with a perpendicular style stained glass window.

The parish is home to the former parishioners of the now-closed St. Stanislaus and St. Francis Xavier churches, also in Nashua.

In 2016 the church became a personal use parish for the Latin Mass St Stanislaus and entrusted to the Priestly Fraternity of Saint Peter.