The church was founded to serve the needs of French-Canadian Catholic immigrants to New Hampshire.

The building is perched atop the plateau that makes up Rimmon Heights, and forms one of the focal points of the Notre Dame neighborhood, along with Lafayette Park across the street.

Marie, Monsignor Pierre Hevey organized the founding of St. Mary's Bank, which is still based at the foot of the hill beneath the church.

In September 2019, the church, and the other buildings on campus were added to the National Register of Historic Places as part of the Sainte Marie Roman Catholic Church Parish Historic District.

This article about a church or other Christian place of worship in New Hampshire is a stub.